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I work out at least 4 times a week, usually 5, despite creaky knees and shoulders left-over from an active youth. A prophylactic dose of ibuprofen has become part of my routine, in the belief that it would help minimize the trauma of exercise. An article in today's NY Times concludes that the ibuprofen does not help, and in fact hinders the body's repair of injured bone and tissue. Here's an excerpt and a link:
Moreover, Warden and other researchers have found that, in laboratory experiments on animal tissues, NSAIDs actually slowed the healing of injured muscles, tendons, ligament, and bones. “NSAIDs work by inhibiting the production of prostaglandins,”substances that are involved in pain and also in the creation of collagen, Warden says. Collagen is the building block of most tissues. So fewer prostaglandins mean less collagen, “which inhibits the healing of tissue and bone injuries,” Warden says, including the micro-tears and other trauma to muscles and tissues that can occur after any strenuous workout or race.