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If you're flying to a specific destination in Asia for your LOB, how many airline choices do you have? Even from LAX, there are only so many ways to arrive in, say, Jakarta, on a specific date.
As for credit cards, if I recall, frequent LOB traveler @outofofficebrb has touted the Chase Sapphire Reserve for its travel insurance and other benefits. If you frequently travel on a particular airline, you may want a co-branded card. I use a Delta co-branded Amex card.