I noticed before I switched to a Helium computer that just putting in the O2 content in a Nitrox only Nitek computer came out very close to the tables.
Once I got the Nitek HE, I was shocked at the Helium penalty, an additional 45 minutes on one dive. I actually sent it back thinking it was defective. I got a nice 2 page letter from Lemar explaining the error of my ways. However, I couldn’t use the computer in Helium mode after that because it gave much longer runtimes than the group I was diving with.