There’s only a couple of places locally here for trimix (my shop isn’t one of them), so I’m toying with the idea of having He at home and topping up at the shop. So as long as the required He PSI is lower than the K cylinder then it should be fine.
Here is both the problem with your approach and the solution--especially if you are working with other divers.
Getting the required He PSI lower than the K bottle is a real problem. You will find yourself venting a lot of expensive helium into the atmosphere--where it will eventually drift off into outer space--in order to get that pressure down. You will need 3-4 (or more) helium bottles at home so you can cascade. If you are doing that, you might as well include the oxygen--it's fraction the cost of the helium.
Believe me, I know this. As a trimix instructor in an area with no trimix for sale, I went through that process for years. I had to drive six hours for the diving, and I could only carry so much gas with me. That meant I was very limited with what I could do with my students on a long weekend.
The solution was simple--buy a good booster. I am not talking some mini-operation that takes tons of drive gas and forever to fill a tank. Spend the bucks for a good electric powered booster. I have mine in a van, and I am able to take enough gas along to take care of fills for me, my students, and my fellow divers. I plug into a motel outlet or the outside outlet of a building near the place where we get the fills topped off. I charge just enough for the gas to break even with the cost of the gas, the cost of getting the gas, etc. There is no no more venting helium into the atmosphere. I estimate it took about two years of monthly trips to pay for the booster completely via the saved gas alone. If I were to charge my friends a little more, I would be running a profit, but I am trying to make diving more affordable for everyone.
BTW, I don't know how things work in your area, but I rent my supply bottles. I drive up to the shop, load the tanks in my van, use them up, and return them. I pay a daily fee while I have the tanks, but it isn't much. That way I can adjust how many tanks I have for each trip depending upon the need, and I don't have to use up so much storage space in my home.