I have read some stuff in the past about anxiety trait . . . and the idea that there are people with high levels of underlying anxiety, and some temperaments that are truly phlegmatic.
A study of cave divers, for example, showed that we generally score very low on trait anxiety, which makes sense -- somebody who is chronically worried isn't going to be very happy about being 1000 feet from the nearest source of air
I've always thought that questionnaire-based testing revealed more about the kind of person that a subject wanted to be...rather than who the subject actually is.
Dealing with stress has a lot to do with concentration and focus. If loud noise, loss of control of a car, gunfire, blood, or a lack of air to breathe can get you to lose concentration and focus, you won't be able to mount an appropriate response to that stress. At that point, you're one step away from not being able to think rationally. Lack of rational thought = panic. A reasonable approach to managing stress better is to simulate it (in real life or through visualization exercises) and gradually turn up the amplitude of the stress, with the aim of desensitizing the loss-of-concentration/focus response. I've read about certain cases in which patients found psychotherapy and self-hypnosis helpful.
FYI, in recent years, scientists have identified a gene called
stathmin which is highly expressed in the amygdala and associated thalamic and cortical structures in the brain. On a cellular level, knocking out the gene disrupts long-term potentiation (process thought to be involved in learning/memory) in amygdala neurons. On an organismic level,
stathmin knockout mice are "less fearful" mice with regard to social interaction, nest-building, and pup-rearing. Humans who have certain genetic polymorphisms in the transcriptional control region of the
stathmin gene (STMN1) show measurable deficits in acoustic startle and cortisol stress response. I haven't cited any of the literature here, but if you do a PubMed search for "stathmin," you'll get lots of hits. It's a very interesting topic in neurobiology.
On a related note, I'm certain that more than one pharmaceutical company is working on a "drug" that modifies stathmin expression, function, or breakdown. Imagine all the different kinds of people who might be able to benefit from such a drug.