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Being tired may be a sub-clinical indication of a bubble load, but still be far away from causing any lasting harm. Of course there could be any number of other things that cause fatigue. So saying fatigue is due to DCS is conjecture. Id just ask if there is anything other than folklore that relates hydration to DCS. I suspect no one will be able to point to a study that shows a correlation. Which does not mean it does not exist. But the foundations may be far less firm than you imagine.
Reasonable amounts of water are safe? Reasonable amounts of many things are safe but not generally claimed to be preventive.
Whether or not water prevents DCS is irrelevant. The point is that it does no harm.
Creatine has a number of known effects and side effects and no clear indication that it's safe for diving.
Terry