Based on another thread and thinking about this subject again I have a couple of questions for anyone who can shed some light!
Haldane/Buhlmann dissolved gas theory is considered to be perfusion limited in that one tissue may be saturated and another nearby tissue may not be but unless that nearby tissue is able to help out via perfusion no gas exchange will occur (according to the theory anyway).
1) Are any theories in mainstream use other than perfusion limited models? I think RGBM and VPM are still perfusion limited aren't they?
2) I think I've read explanations of why Buhlmann added the last several slower compartments but I can't recall what they were now. I'm especially talking about half-lives of 305, 390,498, and 635 minutes. I think I read something along the lines of they were added just to make the calculations come out but that nothing in the human body really has half-lives that slow. Can anyone elaborate or point me in the right direction here.
Thanks!
Haldane/Buhlmann dissolved gas theory is considered to be perfusion limited in that one tissue may be saturated and another nearby tissue may not be but unless that nearby tissue is able to help out via perfusion no gas exchange will occur (according to the theory anyway).
1) Are any theories in mainstream use other than perfusion limited models? I think RGBM and VPM are still perfusion limited aren't they?
2) I think I've read explanations of why Buhlmann added the last several slower compartments but I can't recall what they were now. I'm especially talking about half-lives of 305, 390,498, and 635 minutes. I think I read something along the lines of they were added just to make the calculations come out but that nothing in the human body really has half-lives that slow. Can anyone elaborate or point me in the right direction here.
Thanks!