There are a few minor improvements to other brands. Unfortunately, each one is specific to a single brand and no reg has it all.
Atomic (the guys who design atomic regs used to design scubapro, their absence is part of the reason scubapro became stagnant) have the safest swivel system you can get.
Aqua Lung has a device built into the first stage that will prevent water entering the regulator if it's not screwed onto a tank. I've only been diving 4 years, and I've already had my mk25 serviced one extra time because I got water in the first stage. I wished I had one of these on that day!
Poseidon uses a very different design on their second stages. Desirable if you're diving against a lot of water flow as opposing flow can push the purge on other regs, wasting gas. The only time I've encountered this is in caves. In open water, you generally drift with the flow.
Scubapro also does not stand by their parts for life program. I speak from experience here. I had the local scubapro dealer tell me on the fourth service, that they would no longer honor the program because I had not purchased a full scubapro kit. At the time I purchased my regulators that was not a requirement. The dealer told me it didn't matter, and if I wanted my regs back I had to pay.
I've dove Scubapro Mk25/s600, Aqualung Legend, Poseidon (unknown model) and a few others. For the most part, they all breathed about the same in my opinion. Keep in mind I have never been deeper than 120', so I don't really stress regulators anyway.
So... Mk25/S600 is a good high end reg. It's not suitable (without modification) for cold water where the regulator might freeze. There are lots of similarly priced equally performing regulators out there. Some of which do have a feature or two that is a nice improvement. If you end up diving in cold water, you would probably want to go with a diaphragm regulator (mk25 is piston). Scubapro mk17 is diaphragm I think.