Your pros may be my cons, but the basic difference is that it is downstairs, it is bigger, but has smaller windows. So you have more stair climbing, furthest travel to the dive deck and food, less rocking in the waves.
I have not stayed in a deluxe, just owners and masters. My memory may be a bit faulty...
I forget which rooms are closest to the generators, could be the middle deluxe cabins. But I think the owners gets a bit more wave noise at night. Owners gets no noise from the salon, deluxe are right below it and do get noise from the salon if there is a party going on. If you are napping in the owners you may sleep through the dive bell if they just ring it in the hallway upstairs. I believe owners get lots of engine noise when boat is underway.
we normally pick one of the master rooms, but will be in owners once again on our upcoming trip in may.