I switched to DIN about 16 years ago. At the time, I had yoke tanks, but soon after bought tanks with a pro valve. So, for a while I used the DIN to yoke adapter. It worked fine, but I’ve since switched the yoke tanks over to DIN.
The adapter worked fine, but there are two potential issues with it.
1. The adapter makes it bulkier. In some configurations, that might mean that the reg can poke you in the back. I’ve never had this issue, but if the reg body is inline with the DIN/yoke connector, that could be an issue. Mine has the 90 degree bend, so it hasn’t been an issue.
2. With the adapter, you have double the o-rings at the connection. One in the tank valve, and one at the regulator DIN connection. Not really a huge concern as long as you carry the appropriate spare o-rings, also, this is no different than using a pro valve with a yoke reg.
I prefer DIN. Connection is more positive, and o-ring is more secure. Yoke o-rings tend to blow out with some degree of regularity. I can’t recall ever having a DIN o-ring blowout. One thing, though on the o-rings. Yoke o-rings are one size, but there are two DIN o-ring sizes. So the unprepared yoke diver can reasonably expect a fellow diver to have a spare, but it’s a lot less likely with a DIN. Usually not needed, so this may be a wash. I carry a small kit with me of the o-rings I might need: DIN, flashlights, computer, transmitter, and hoses. I even carry a few yoke o-rings to bail out my friends who dive yoke.