Does High PO2 = High CO2?

[Mr. Bubble]

.....

 

[Mr. Bubble]

TSandM,

are you in anyway related to H.A.L. from 2001 space oddity?


Just kidding....

B

 

[z3r0c00l]

Daisy, Daaisyy, giiiiivvvveeeee meeeeeeeeeeeee yyyyyyooooooouuuuuuuurrrrrrrrrrrrrrrrrrrrrrrr

 

[Gene_Hobbs]

Thanks knotical, I had not read the Bookspan/ Lanphier version.

I have always been partial to how Lanphier and Camporesi describe Lanphier's (1-4) work at NEDU to answer the question 'why don't divers breathe enough?'

1. Higher Inspired Oxygen (PiO2) at 4 ata (404 kPa) accounted for not more than 25% of the elevation in End Tidal CO2 (etCO2) above values found at the same work rate when breathing air just below the surface.
2. Increased Work of Breathing accounted for most of the elevation of PACO2 (alveolar gas equation) in exposures above 1 ata (101 kPa), as indicated by the results when helium was substituted for nitrogen at 4 ata (404 kPa).
3. Inadequate ventilatory response to exertion was indicated by the fact that, despite resting values in the normal range, PetCO2 rose markedly with exertion even when the divers breathed air at a depth of only a few feet.

Since you mention treatments... Excess CO2 is something we try to avoid through our method of providing Oxygen (hoods, masks, tee piece, etc) as it is usually increased dead space or work of breathing that are our main concerns for CO2 accumulation and not our pO2.

References:
1. Lanphier. Nitrogen-Oxygen Mixture Physiology, Phases 1 and 2. NEDU Report 1955-07. RRR ID: 3326
2. Lanphier, Lambertsen, and Funderburk. Nitrogen-Oxygen Mixture Physiology - Phase 3. End-Tidal Gas Sampling System. Carbon Dioxide Regulation in Divers. Carbon Dioxide Sensitivity Tests. NEDU Report 1956-02. RRR ID: 3327
3. Lanphier. NITROGEN-OXYGEN MIXTURE PHYSIOLOGY. PHASE 4. CARBON DIOXIDE SENSITIVITY AS A POTENTIAL MEANS OF PERSONNEL SELECTION. PHASE 6: CARBON DIOXIDE REGULATION UNDER DIVING CONDITIONS NEDU Report 1958-07. RRR ID: 3362
4. Lanphier. Nitrogen-Oxygen Mixture Physiology. Phase 5. Added Respiratory Dead Space (Value in Personnel Selection tests) (Physiological Effects Under Diving Conditions). NEDU Report 1956-05. RRR ID: 3809

There is also some interesting work in the repository from Herman Rahn and Bill Hamilton's PhD thesis that relate to Nitrogen-Oxygen physiology.