I am not a big fan of medications for seasickness. I think they may affect your reasoning faculties and reaction times may be affected, like alcohol, etc. I have seen people with patches on doing liveaboards, don't know if they worked or not.
I am a fan of ginger tablets. They are natural and settle a stomach for most people.
My feeling is that people who are prone to seasickness need to:
*Stay up in the fresh air, don't ever go below or indoors if you get that funny feeling
*Focus on the horizon if you get a little woozy
*Stay busy, talk to other people, fix your gear, etc. (it takes your mind off of it and works most of the time)
*Get it in your head that you don't have to be seasick. If you are sure you are going to get sick, then you will.
*If you do get sick, do it over the side, not in the head.
Some people on liveaboards feel sick the first day or two but their bodies adjust and they are fine the rest of the week. I don't have any problems with it but I gradually worked my way into it. Sitting on a little rocking boat for an hour surface interval just about killed me more that once. I found liveaboards to be waaaaay better. My first liveaboard was the Nekton because I didn't know how my body would react. I took a box of ginger tablets with me and only used them the first two days (I doubt I even needed them). Since then I have had lots of trips on rocking boats, some where several people were hanging over the rails, and I never felt queasy. I really think my body learned to adapt over time to the motion - plus I now expect NOT to get sick.
Just my 2 cents.
robin