I think that this thread is suffering from mission creep, and we are coming up with all sorts of unusual scenarios involving hypoxic dil, deco, atypical configurations, etc... I don't think that a once a year single tank vacation diver is going to be instabuddied with someone diving an expedition grade rig doing some major dive.
Well... My CCR buddy and I dived the Oriskany a few months ago. There was one other tech diver on the boat and everyone else were single tank, OC, recreational divers. My buddy intended to go to the bottom (215') at some point during our dive. So, he was setup with hypoxic dil and was carrying 2 slung cylinders (1 bottom mix and 1 deco gas). The rec divers would be exploring the ship's tower which starts at around, roughly 80 feet.
If I had turned up sick one morning or something like that, he still would have been out on that boat, guaranteed.
All it takes is a dive site with stuff to see at a lot of different depths (e.g. a wall dive, a reef with a lot of relief, or... an artificial reef with a lot of relief).
I'm not saying he would have taken on an insta-buddy in that situation. But, who really knows what kinds of setups people will find themselves sitting next to on a boat?
Anyway, as I have been saying since the start of this thread. The only simple answer is a pre-dive conversation. Beyond that, it's the same as it always is. Every diver has to use their best judgment based on the info they have at the time. But, if an OC diver comes upon a CCR diver in the water and thinks about touching ANYTHING on that diver's rig, they better be absolutely positive that the alternative is worse.
In the face of ignorance regarding the diver's rig, it seems to me that all you can do is verify they are (really and truly) unresponsive or, possibly, simply out of their gourd (narced? panicked? having a heart attack?), and, in that case, get them to the surface in a controlled fashion. But, you better be SURE that the alternative is worse before you physically take control of another diver and force them to the surface. And you also better be SURE that you can do it without endangering yourself. Don't turn 1 statistic into 2.
An alternative to being sure and taking control of them would be, circumstances permitting, keep your distance and shoot a bag. Keep an eye on them and hope the boat crew is alert enough to send help when they see your bag. Keep yourself safe (including minding your own gas level and NDL), no matter what.