Nitrogen isn't a noble gas. It's not chemically inert. It is narcotic.
Helium is a noble gas. It is chemically inert. It is not narcotic.
Oh, Lordie... let's get this stuff straight now, before it gets
really confusing.
"Noble" gasses are those with "full" electron "layers" and are therefore chemically inert. This has
nothing to do with narcosis, however.
Nitrogen (N
2), though not a noble gas and not
chemically inert, is "
physiologically inert" in that it isn't changed chemically by human body processes. It is dissolved and released as N
2 and doesn't change while it's in the body.
Compressed gas narcosis, commonly called "nitrogen" narcosis, is a property of all gasses; some are just more narcotic than others. The Narcotic properties of a gas appear to be fairly closely correlated with the gas's solubility in lipids (fats & oils). Helium, for example, is practically insoluble in lipids and has very little narcotic effect, while Argon - another noble gas - is very soluble in lipids and is very narcotic. Nitrogen is in between. Just exactly why gasses that are "inert" cause narcosis isn't well understood, but it appears they somehow change the conductivity - and therefore the ability to transmit impulses - in nerves (or in the myelin sheath) - by physical (as opposed to chemical) interference.
Looking at Oxygen, it's about twice as soluble in lipids as nitrogen, so one might infer that Oxygen should therefore be about twice as narcotic as Nitrogen and that Nitrox should be a bit more narcotic than air... but... since oxygen is not inert, and is both metabolized in the body and scavenged by hemoglobin, nerve tissue titers (concentrations) are typically about a sixth what would be expected if oxygen were inert like Nitrogen. So, perhaps we should expect about a third the narcotic effect from oxygen as we do from nitrogen, and Nitrox should be slightly less narcotic than air
Personally, I like the wording in SSI's Nitrox materials: "It is best not to assume any reduction in narcosis" when moving to Nitrox from air.
Rick