1.)
4.) If the cylinder is O2 clean and is then filled with Grade E air, then the cylinder is no longer considered O2 clean. Is this really the case? Does one, two, or ten Grade E air fills push enough contaminants in to your cylinder to cause it to lose its O2 clean status? Probably not. Dick @ Global estimates that greater than 70% of dive shops produce compressed air that meets or exceeds oxygen compatible air requirements...they might not even know it.
I work for a lab that tests supplied breathing air. It's more like 100%, and that's without hyperfilters.